Nicolas G Bazan Selected Research

Ischemic Stroke

4/2023	cRel and Wnt5a/Frizzled 5 Receptor-Mediated Inflammatory Regulation Reveal Novel Neuroprotectin D1 Targets for Neuroprotection.
1/2023	Novel Lipid Mediators as a Promising Therapeutic Strategy for Ischemic Stroke.
1/2023	Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection.
10/2020	Blocking pro-inflammatory platelet-activating factor receptors and activating cell survival pathways: A novel therapeutic strategy in experimental ischemic stroke.
8/2018	Docosanoids Promote Neurogenesis and Angiogenesis, Blood-Brain Barrier Integrity, Penumbra Protection, and Neurobehavioral Recovery After Experimental Ischemic Stroke.
1/2017	Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke.
1/2017	Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury.
2/2014	Docosahexaenoic acid complexed to albumin provides neuroprotection after experimental stroke in aged rats.
1/2013	Acute treatment with docosahexaenoic acid complexed to albumin reduces injury after a permanent focal cerebral ischemia in rats.
9/2012	Docosahexaenoic acid complexed to human albumin in experimental stroke: neuroprotective efficacy with a wide therapeutic window.

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Nicolas G Bazan Research Topics

Disease

23	Stroke (Strokes) 10/2023 - 06/2002
21	Brain Ischemia (Cerebral Ischemia) 01/2017 - 11/2002
19	Alzheimer Disease (Alzheimer's Disease) 03/2023 - 06/2002
15	Inflammation (Inflammations) 01/2024 - 08/2002
15	Ischemic Stroke 04/2023 - 10/2002
11	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 10/2023 - 11/2002
11	Ischemia 01/2017 - 10/2002
10	Retinal Degeneration 11/2023 - 06/2004
10	Macular Degeneration (Age-Related Maculopathy) 10/2023 - 08/2005
9	Infarction (Infarctions) 11/2020 - 07/2002
8	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 08/2005
7	Neuroinflammatory Diseases 12/2023 - 05/2005
6	Cognitive Dysfunction 03/2023 - 10/2005
6	Seizures (Absence Seizure) 05/2020 - 01/2002
6	Wounds and Injuries (Trauma) 12/2014 - 04/2004
5	COVID-19 01/2022 - 08/2020
4	Brain Injuries (Brain Injury) 10/2023 - 02/2003
4	Neoplasms (Cancer) 01/2021 - 03/2004
4	Epilepsy (Aura) 01/2016 - 06/2002
4	Retinitis Pigmentosa (Pigmentary Retinopathy) 10/2013 - 05/2006
4	Choroidal Neovascularization 01/2013 - 03/2010
4	Nervous System Diseases (Neurological Disorders) 09/2005 - 06/2002
4	Hypoxia (Hypoxemia) 05/2004 - 08/2002
3	Neuralgia (Stump Neuralgia) 01/2021 - 11/2010
3	Brain Edema (Cerebral Edema) 07/2015 - 01/2005
3	Dry Eye Syndromes (Dry Eye Syndrome) 02/2010 - 09/2005
3	Sleep Deprivation 05/2006 - 02/2006
3	Pathologic Processes 04/2006 - 08/2004
2	Pain (Aches) 01/2024 - 11/2002
2	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2024 - 11/2011
2	Atrophy 01/2023 - 11/2011
2	Cerebral Hemorrhage 04/2022 - 05/2020
2	Retinal Diseases 01/2022 - 03/2014
2	Thrombocytopenia (Thrombopenia) 11/2021 - 01/2021
2	Virus Diseases (Viral Diseases) 10/2021 - 01/2021
2	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2021
2	Temporal Lobe Epilepsy 01/2016 - 09/2011
2	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2015 - 10/2013
2	Blindness (Hysterical Blindness) 03/2015 - 03/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2015 - 07/2002
2	Necrosis 10/2013 - 04/2004
2	Deafness (Deaf Mutism) 03/2013 - 03/2010
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 07/2012 - 10/2003
2	Eye Diseases (Eye Disease) 11/2011 - 05/2007

Drug/Important Bio-Agent (IBA)

32	LipidsIBA 01/2024 - 08/2002
30	Docosahexaenoic AcidsIBA 11/2020 - 10/2002
26	protectin D1IBA 10/2023 - 04/2005
13	Retinaldehyde (Retinal)IBA 11/2023 - 10/2003
12	Retinal Pigments (Pigments, Visual)IBA 04/2023 - 08/2005
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2003
12	Platelet Activating FactorIBA 10/2020 - 07/2002
8	Phospholipids (Phosphatides)FDA LinkGeneric 01/2021 - 07/2002
8	EnzymesIBA 01/2021 - 06/2002
7	CytokinesIBA 04/2023 - 10/2003
7	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 11/2002
7	ProstaglandinsIBA 01/2018 - 06/2002
6	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2023 - 01/2005
6	platelet activating factor receptorIBA 01/2023 - 04/2004
6	Arachidonic Acid (Vitamin F)IBA 01/2018 - 06/2002
5	AlbuminsIBA 02/2014 - 11/2002
4	Phospholipases (Phospholipase)IBA 10/2023 - 02/2003
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2023 - 10/2003
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 10/2003
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2017 - 02/2006
4	Glutamic Acid (Glutamate)FDA Link 01/2017 - 01/2002
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 09/2011 - 08/2002
4	Secretory Phospholipases A2IBA 05/2007 - 07/2002
4	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 05/2005 - 06/2002
4	Phospholipases A2 (Phospholipase A2)IBA 04/2005 - 08/2002
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2024 - 11/2010
3	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 12/2023 - 10/2005
3	Nonesterified Fatty Acids (NEFA)IBA 01/2023 - 11/2002
3	Peptides (Polypeptides)IBA 12/2021 - 08/2002
3	Oxygen (Dioxygen)IBA 01/2021 - 10/2002
3	LAU 0901IBA 01/2021 - 04/2004
3	Neuroprotective AgentsIBA 01/2013 - 11/2002
3	Human Serum Albumin FDA LinkGeneric 09/2012 - 11/2002
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2024 - 09/2004
2	EndocannabinoidsIBA 01/2024 - 06/2006
2	AcidsIBA 01/2024 - 10/2023
2	Amyloid (Amyloid Fibrils)IBA 03/2023 - 12/2021
2	InterferonsIBA 01/2022 - 07/2015
2	Messenger RNA (mRNA)IBA 11/2021 - 05/2020
2	VaccinesIBA 11/2021 - 01/2021
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2021 - 12/2014
2	RNA (Ribonucleic Acid)IBA 01/2021 - 10/2003
2	ChemokinesIBA 01/2021 - 11/2011
2	Cell Surface ReceptorsIBA 11/2020 - 04/2004
2	AntioxidantsIBA 09/2020 - 08/2002
2	SaltsIBA 01/2017 - 07/2012
2	SodiumIBA 01/2017 - 07/2012
2	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 12/2004
2	EstersIBA 01/2017 - 07/2012
2	Myosin-Light-Chain KinaseIBA 07/2015 - 10/2013
2	Isoflurane FDA LinkGeneric 02/2014 - 02/2009
2	interstitial retinol-binding proteinIBA 10/2013 - 04/2013

Therapy/Procedure

19	Therapeutics 01/2024 - 11/2002
4	Sutures (Suture) 02/2014 - 01/2005
3	Lasers (Laser) 01/2013 - 03/2010
2	Refractive Surgical Procedures 11/2017 - 02/2010